5-Azacytosine CAS 931-86-2 Purity ≥98.0% (HPLC) Factory High Purity

Short Description:

Chemical Name: 5-Azacytosine

CAS: 931-86-2

Appearance: White or Off-White Crystalline Powder

Purity: ≥98.0% (HPLC)

High Quality, Commercial Production

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Product Detail

Product Tags

931-86-2 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of 5-Azacytosine (CAS: 931-86-2) with high quality, commercial production. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase 5-Azacytosine, Please contact: alvin@ruifuchem.com

931-86-2 - Chemical Properties:

Name	5-Azacytosine
Synonyms	Azacitidine; 5-AzaC; 2-Amino-4-hydroxy-1,3,5-triazine; 4-Amino-1,3,5-triazin-2(1H)-one
CAS Number	931-86-2
Stock Status	In Stock, Commercial Production
Molecular Formula	C3H4N4O
Molecular Weight	112.09
Melting Point	>300℃(lit.)
Density	1.86
COA & MSDS	Available
Origin of Product	Shanghai, China
Product Categories	Pharmaceutical Intermediates
Brand	Ruifu Chemical

931-86-2 - Specifications:

Item	Specifications	Results
Appearance	White or Off-White Crystalline Powder	White Crystalline Powder
Loss on Drying	≤0.50%	0.09%
Moisture (K.F)	≤0.50%	0.39%
Residue on Ignition	≤0.20%	0.12%
Heavy Metals	≤20ppm	<20ppm
6-Methyl-5-Azacytosine	≤1.00%	0.0%
6-Amino-5-Azacytosine	≤1.00%	0.28%
2,4-Diaminotriazine	≤0.80%	0.0%
2,4,6-Traminotriazine	≤0.50%	0.0%
Impurity at RRT 1.5	≤0.80%	0.0%
All Other Impurities	≤0.20%	0.0%
Purity / Analysis Method	≥98.0% (HPLC)	99.72%
Assay / Analysis Method	≥98.0% (Titration)	100.51%
Infrared Spectrum	Conforms to Structure	Conforms
Conclusion	The product has been tested and complies with the given specifications

931-86-2 - Package & Storage:

Package: Bottle, Aluminum foil bag, 25kg/Cardboard Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture.

931-86-2 - Advantages:

931-86-2 - FAQ:

931-86-2 - Risk and Safety:

Risk Codes R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
S36 - Wear suitable protective clothing.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany 3
RTECS XZ2854300
HS Code 2934999099

931-86-2 - Application:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 5-Azacytosine (CAS: 931-86-2) with high quality, widely used in organic synthesis, synthesis of pharmaceutical intermediates and Active Pharmaceutical Ingredient (API) synthesis.

5-Azacytosine (CAS: 931-86-2) can inhibits the growth of Escherichia coli and used as the most effective cytosine mimics for the design of novel antiviral and anti-tumor drug candidates. 5-Azacytidine is a chemical analog of cytidine and acts as a hypomethylating agent. 5-Azacytidine is a DNA methyltransferase inhibitor that induces the demethylation and reactivation of silenced genes.

931-86-2 - Method of Analysis:

Items of Analysis (Revision # 3 Date 02/16/2008)
1. Description: White or Off-White Crystalline Powder (View by eye)
2. Loss on drying: 105℃, 4h
3. Heavy metals: nmt 20ppm (According to Method III of Heavy Metals, CP2005 Excursus 8H) .
4. Melting point: >300℃ (According to Method III of CP2005 Excursus VI C) .
5. Chromatographic purity (HPLC): nlt 98.00%
Instrument: SPD-10Avp
Column: Venusil MP-C18 250L*4.6
Mobile phase: 6.3g of ammonium formate in 1000mL, adjust pH to 2.8 with formic acid, Mix well and filter.
Wavelength: 240nm
Procedure: Approximately 0.02 g to 100-mL volumetric flask, dissolve and dilute with mobile phase to volume, and mix, then filter the solution as the test solution.
Inject a volume (about 20 μL) of the sample into the chromatograph, determine the percentage of the major peak by area normalization, record the chromatograms and calculate the peak responses for the major peaks.